The exam facts, the calculation formulas and the key facts from each study note, on one printable page. Exam facts are as at 12 Oct 2026 from pebc.ca. PEBC provides its own formula sheet at the exam; these are standard formulas for practice.
PEBC Prep is an independent study aid. It is not affiliated with, endorsed by or connected to The Pharmacy Examining Board of Canada (PEBC). 'PEBC' is used only to describe the examination. All questions are original practice material, not past or real exam questions. Educational practice material for exam preparation only. Not medical advice and not a substitute for current product monographs, clinical guidelines or professional judgement. Questions have not yet been reviewed by a licensed pharmacist.
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Most questions put these facts into a patient case.
| Format | 200 questions (150 scored + 50 pretest), one section, 260 minutes; four options a-d | pebc.ca FAQ; Part I (MCQ) |
| Blueprint | 1A Clinical Care 50% · 1B Distribution 20% · 2 Knowledge & Expertise 11% · 3 Communication & Collaboration 4% · 4 Leadership & Stewardship 3% · 5 Professionalism 12% | PEBC Blueprint Ver. 03-2026 |
| Pace | 1.3 minutes a question | 260 ÷ 200 |
| Result | Pass or fail only; no score is reported; unsuccessful candidates receive feedback by competency area, about 8 weeks after results | Examination Scoring and Results |
| Attempts | 4 per part (4th after remediation); lifetime cap 8 | Examination Scoring and Results |
| Fee | C$870 for Part I (2027 fee) | Examination Dates and Fees |
| Aids | On-screen calculator and the formula sheet provided only; closed book | Part I (MCQ) |
| Creatinine clearance (Cockcroft-Gault, SI) | (140 − age) × weight (kg) × 1.23 ÷ SCr (µmol/L); × 0.85 for females |
| Body surface area (Mosteller) | √[height (cm) × weight (kg) ÷ 3600] |
| Ideal body weight (Devine) | male 50 kg, female 45.5 kg, + 2.3 kg per inch over 5 feet |
| Adjusted body weight | IBW + 0.4 × (TBW − IBW) |
| Dilution | C1 × V1 = C2 × V2 |
| Infusion rate | mL/h = volume ÷ hours; drops/min = mL/min × drop factor |
| Absolute risk reduction, NNT | ARR = CER − EER; NNT = 1 ÷ ARR, rounded up |
| Relative risk, RRR | RR = EER ÷ CER; RRR = 1 − RR |
| Odds ratio | (a × d) ÷ (b × c) |
| Sensitivity, specificity | TP ÷ (TP + FN); TN ÷ (TN + FP) |
| Predictive values | PPV = TP ÷ (TP + FP); NPV = TN ÷ (TN + FN) |
Worked examples: PEBC calculations questions.
Hypertension and lipid management are core Part I clinical topics: expect patient scenarios asking for the next drug, a target, a monitoring step or an interaction, using Hypertension Canada's 2025 primary care guideline and the 2021 CCS dyslipidemia guidelines.
Heart failure, atrial fibrillation, coronary disease and anticoagulation produce some of the highest-stakes Part I items: drug selection, DOAC dosing, warfarin interactions and secondary prevention, with Canadian (CCS, Thrombosis Canada) guidance and product monographs.
Endocrine items cover diabetes therapy and safety (hypoglycemia, sick days, renal dosing), thyroid replacement, osteoporosis, contraception and menopause, applying Diabetes Canada, ATA, Osteoporosis Canada and SOGC guidance.
Respiratory items test the CTS 2021 asthma and 2023 COPD updates, inhaler technique, exacerbation action, smoking cessation pharmacotherapy and allergic rhinitis, often in patient cases with control criteria to interpret.
Infection items test first-line antibiotic choice by site and patient, stewardship (when not to treat), key interactions and adverse effects, STI treatment and the Canadian Immunization Guide, using AMMI Canada, Bugs & Drugs, PHAC and NACI sources.
Neuro-psych items cover depression (CANMAT 2023), anxiety, bipolar disorder and lithium, antipsychotic safety and clozapine, ADHD, insomnia, opioid and alcohol use disorder, epilepsy, Parkinson disease, dementia and migraine, with many safety-critical interactions.
GI, renal and hepatic items test reflux and ulcer care, IBD and IBS, constipation and nausea, CKD drug stewardship, electrolyte problems and dosing in liver disease, often as medication reviews in older adults.
Pain and rheumatology items test analgesic choice and limits, opioid safety under the 2017 Canadian guideline, neuropathic pain, osteoarthritis, rheumatoid arthritis drug monitoring and gout management.
Self-care items test when to treat with nonprescription products and when to refer: coughs and colds, eye and ear complaints, skin conditions, GI symptoms, emergency contraception, vaginal symptoms, pediatric fever and natural health products.
These items apply therapeutics to pediatrics, older adults, pregnancy and lactation, oncology supportive care, urology, ophthalmology and transplant medicine, where the same drug can be right for one patient and harmful for another.
Distribution items test how a pharmacist assesses and processes prescriptions: completeness and validity, dose and interaction checks, look-alike names, dangerous abbreviations, labelling, substitution, transfers, refills and compliance packaging.
Calculation items appear throughout Part I: weight-based and BSA dosing, creatinine clearance, IV rates, concentrations and dilutions, electrolytes, days' supply, compounding and opioid conversions. PEBC supplies an on-screen calculator and a formula sheet.
These items test NAPRA's non-sterile and sterile compounding standards, hazardous drug handling, beyond-use dating, storage and cold chain, recalls, shortages, narcotic inventory control and product verification.
Knowledge and Expertise items test critical appraisal and biostatistics: study designs and bias, NNT and risk measures, confidence intervals and p-values, diagnostic test statistics, meta-analysis, pharmacoeconomics and answering drug information requests.
Communication and Collaboration is about 4% of Part I but much more of the OSCE. MCQ items test teach-back, motivational interviewing, interprofessional communication, documentation, medication reconciliation and patient-centred conversations.
Leadership and Stewardship (about 3%) items test the pharmacist's role in population health: antimicrobial stewardship, screening, vaccination programs, harm reduction, health equity, travel health and safe medication disposal.
Law items test federal drug law (Food and Drugs Act, CDSA and its regulations, Cannabis Act, Vanessa's Law), NAPRA schedules, privacy, scope of practice and record-keeping. Provincial rules vary, so PEBC items usually turn on federal law or widely shared standards.
These professionalism items test ethical principles in practice, conflicts of interest, conscientious objection, boundaries, equity and cultural safety, and medication safety systems: disclosure, incident reporting, just culture and quality improvement.
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