PS, 64, asks for an over-the-counter acid reducer. He has had heartburn for 3 months, now with food sticking in his throat and a 5 kg weight loss he did not intend. Which of the following is the most appropriate recommendation?
Dysphagia and unintentional weight loss are alarm features that may indicate esophageal stricture or cancer, and new symptoms after about age 60 also call for investigation. Canadian guidance advises referral for prompt endoscopic evaluation rather than self-treatment. Acid suppression could mask symptoms and delay diagnosis. Source: Moayyedi PM et al. ACG and CAG Clinical Guideline: Management of Dyspepsia (Am J Gastroenterol 2017;112:988); omeprazole nonprescription labelling (DPD, checked 2026).
Self-treating reflux in a patient with alarm symptoms.
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