Four adults have confirmed systolic BP between 130 and 139 mm Hg on home monitoring and none takes antihypertensive drugs. For which person does the 2025 guideline recommend starting pharmacotherapy now?
For systolic BP 130-139 mm Hg, the guideline recommends drug therapy only for people at high cardiovascular risk: established cardiovascular disease, diabetes (type 1 or 2), chronic kidney disease (eGFR below 60 or albuminuria), 10-year Framingham risk of 20% or more, or age 75 or older. The others should start lifestyle changes with reassessment in 3-6 months; a 12% Framingham risk is below the 20% threshold. Source: Hypertension Canada primary care guideline (CMAJ 2025;197:E549), Box 1 High cardiovascular disease risk conditions.
Treating any risk factor as 'high risk' rather than using the listed conditions.
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